76000MONTH2022•VOLXXXISSUEXXXXscience.orgSCIENCEPHOTO:CREDITGOESHEREASSHOWN;CREDITGOESHEREASSHOWNThehealthyhumanbodyishometoanabundanceofbacteria,viruses,andfungithatareacquiredinearlypostnatallife.Thebulkofthemicrobiomeisinthegut,butdistinctmicrobialcommunitiesexistontheskinandinthemouth,nose,lungs,andgenitaltract.Thehumanmicrobiomehasimportantrolesinmaintaininghomeostasis,anddisruptionofmicrobialcolonizationofaninfanthassystemiceffectsthatmayinfluencehealthlaterinlife,po-tentiallypromotingthedevelopmentofautoimmunity,allergies,metabolicdiseases,andevencancer.Studiesofmicrobialnichesintheskinhaverevealedthattheyareintegraltotheskin’smultifacetedbarrier...
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